Vessel and tissue recognition during third-space endoscopy using a deep learning algorithm

Alanna Ebigbo, Robert Mendel, Neal Shahidi, Friederike Prinz, Carola Fleischmann, Christoph Römmele, Stefan Karl Goelder, Georg Braun, David Rauber, Tobias Rueckert, Luis A de Souza Jr, Joao Papa, Michael Byrne, Christoph Palm, Helmut Messmann

In this study, we aimed to develop an artificial intelligence clinical decision support solution to mitigate operator-dependent limitations during complex endoscopic procedures such as endoscopic submucosal dissection and peroral endoscopic myotomy, for example, bleeding and perforation. A DeepLabv3-based model was trained to delineate vessels, tissue structures and instruments on endoscopic still images from such procedures. The mean cross-validated Intersection over Union and Dice Score were 63% and 76%, respectively. Applied to standardised video clips from third-space endoscopic procedures, the algorithm showed a mean vessel detection rate of 85% with a false-positive rate of 0.75/min. These performance statistics suggest a potential clinical benefit for procedure safety, time and also training.

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